Kazuei Igarashi Selected Research

Brain Infarction

10/2020	Structural change and degradation of cytoskeleton due to the acrolein conjugation with vimentin and actin during brain infarction.
2/2020	Assessing acrolein for determination of the severity of brain stroke, dementia, renal failure, and Sjögren's syndrome.
1/2019	Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
1/2018	Protective Effects of Brain Infarction by N-Acetylcysteine Derivatives.
6/2017	Time dependent transition of the levels of protein-conjugated acrolein (PC-Acro), IL-6 and CRP in plasma during stroke.
1/2017	Correlation between brain damage, associated biomarkers, and medication in psychiatric inpatients: A cross-sectional study.
10/2016	Decrease in acrolein toxicity based on the decline of polyamine oxidases.
4/2016	Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging.
1/2016	Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke.
1/2016	Recent Progress in Analytical Methods for Determination of Urinary 3-Hydroxypropylmercapturic Acid, a Major Metabolite of Acrolein.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Kazuei Igarashi Research Topics

Disease

23	Brain Infarction 10/2020 - 04/2009
22	Stroke (Strokes) 10/2021 - 12/2005
9	Carcinoma (Carcinomatosis) 01/2020 - 05/2002
8	Thrombosis (Thrombus) 12/2020 - 01/2011
7	Infarction (Infarctions) 12/2020 - 10/2009
7	Chronic Kidney Failure (Chronic Renal Failure) 10/2016 - 05/2003
5	Renal Insufficiency (Renal Failure) 02/2020 - 05/2003
5	Dementia (Dementias) 02/2020 - 01/2014
5	Neuroblastoma 01/2016 - 01/2012
5	Alzheimer Disease (Alzheimer's Disease) 10/2015 - 01/2012
4	Cognitive Dysfunction 10/2015 - 01/2012
4	Neoplasms (Cancer) 01/2013 - 01/2002
2	Inflammation (Inflammations) 01/2021 - 01/2013
2	Ischemic Stroke 12/2020 - 01/2018
2	Body Weight (Weight, Body) 06/2020 - 12/2002
2	Mood Disorders (Mood Disorder) 01/2020 - 01/2017
2	Schizophrenia (Dementia Praecox) 01/2020 - 01/2017
2	Nervous System Diseases (Neurological Disorders) 01/2018 - 09/2007
2	Autoimmune Diseases (Autoimmune Disease) 01/2017 - 10/2015
2	Atherosclerosis 01/2015 - 03/2013
2	Carotid Artery Diseases 01/2011 - 08/2010
2	Seizures (Absence Seizure) 11/2009 - 09/2007
2	Breast Neoplasms (Breast Cancer) 10/2006 - 11/2002
1	Rheumatoid Arthritis 03/2021
1	Melanosis (Freckles) 10/2020
1	Cerebral Infarction 01/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020
1	Wounds and Injuries (Trauma) 12/2018
1	Ischemia 01/2018
1	Bacterial Infections (Bacterial Infection) 11/2017
1	Hemorrhagic Stroke 06/2017
1	Hemorrhage 06/2017
1	Erythema 03/2016
1	Polyps 12/2014
1	Hypoxia (Hypoxemia) 04/2014
1	Vascular Remodeling 04/2014

Drug/Important Bio-Agent (IBA)

42	Acrolein (Aqualin)IBA 10/2021 - 05/2003
23	Proteins (Proteins, Gene)FDA Link 10/2020 - 05/2003
21	PolyaminesIBA 01/2021 - 05/2003
14	Biomarkers (Surrogate Marker)IBA 10/2021 - 12/2005
10	Interleukin-6 (Interleukin 6)IBA 02/2020 - 04/2009
8	Oxidoreductases (Dehydrogenase)IBA 01/2018 - 05/2003
6	Acetylcysteine (Siran)FDA LinkGeneric 12/2020 - 10/2009
6	EnzymesIBA 01/2018 - 10/2009
6	Polyamine OxidaseIBA 01/2018 - 12/2005
5	Glutathione (Reduced Glutathione)IBA 08/2020 - 04/2012
4	SpermineIBA 12/2018 - 05/2003
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 01/2009
4	C-Reactive ProteinIBA 01/2017 - 09/2011
3	Rose BengalIBA 01/2018 - 10/2009
3	N-Methylaspartate (NMDA)IBA 01/2016 - 09/2007
3	hydroxypropyl methacrylateIBA 10/2015 - 04/2012
3	Amyloid (Amyloid Fibrils)IBA 10/2015 - 01/2012
3	CreatinineIBA 10/2015 - 04/2012
2	HDL LipoproteinsIBA 06/2020 - 01/2020
2	HDL CholesterolIBA 06/2020 - 01/2015
2	LipidsIBA 01/2020 - 12/2014
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2018 - 01/2016
2	Antipsychotic Agents (Antipsychotics)IBA 01/2017 - 01/2015
2	Immunoglobulins (Immunoglobulin)IBA 01/2017 - 10/2015
2	Biological ProductsIBA 10/2015 - 09/2007
2	Memantine (Namenda)FDA Link 07/2013 - 01/2012
2	SpermidineIBA 01/2013 - 10/2009
2	Pharmaceutical PreparationsIBA 01/2012 - 10/2006
2	Neuroprotective AgentsIBA 11/2009 - 09/2007
1	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 01/2021
1	GlycosaminoglycansIBA 12/2020
1	Proteoglycans (Proteoglycan)IBA 12/2020
1	Glycoproteins (Glycoprotein)IBA 12/2020
1	OligosaccharidesIBA 12/2020
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 10/2020
1	TubulinIBA 10/2020
1	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA 10/2020
1	VimentinIBA 10/2020
1	CholesterolIBA 06/2020
1	Triglycerides (Triacylglycerol)IBA 06/2020
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Blood Glucose (Blood Sugar)IBA 01/2020
1	Protein SIBA 01/2019
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 12/2018
1	Urokinase Plasminogen Activator ReceptorsIBA 12/2018
1	TransferasesIBA 01/2018
1	EstersIBA 01/2018
1	AcetaldehydeIBA 11/2017
1	Ligases (Synthetase)IBA 04/2016
1	PolyphenolsIBA 01/2015
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2015
1	Therapeutic UsesIBA 01/2015
1	NitrogenIBA 12/2014
1	Peptides (Polypeptides)IBA 12/2014
1	Phosphates (Orthophosphate)IBA 12/2014
1	CalciumIBA 12/2014
1	Nucleic AcidsIBA 12/2014
1	PolyphosphatesIBA 12/2014
1	CarbonIBA 12/2014
1	Adenosylmethionine DecarboxylaseIBA 04/2014
1	actinomycin D1IBA 04/2014
1	Pemetrexed (MTA)FDA Link 01/2014

Therapy/Procedure

2	Intravenous Injections 07/2013 - 11/2009